USPTO Patents Application 09972467

q Page 1 of 7

OIPE

RAW SEQUENCE LISTING DATE : 10/19/2001

PATENT APPLICATION: US/09/972,467 TIME: 12:32:07

Input Set : A:\PC10850A.app

Output Set: N:\CRF3\10192001\l972467.raw

3 <110> APPLICANT: PFIZER INC.

5 <120> TITLE OF INVENTION: ADAMTS POLYPEPTIDES , NUCLEIC ACIDS ENCODING THEM, AND

6 USES THEREOF

8 <130> FILE REFERENCE: PC10850A a
C--> 10 <140> CURRENT APPLICATION NUMBER: US/09/972,467 QV^
C--> 11 <141> CURRENT FILING DATE: 2001-10-05 ^

13 <160> NUMBER OF SEQ ID NOS : 10 V
15 <170> SOFTWARE: Patentln Ver. 2.1

17 <210> SEQ ID NO: 1

18 <211> LENGTH: 5949

19 <212> TYPE: DNA

20 <213> ORGANISM: Human
22 <400> SEQUENCE: 1

2 3 ccggaattcc cgggtcgacc cacgcgtccg gccccccatt caagaagccg ctcagctatc 60

24 ccggccagca cagggcgccc ggcgcgcctc ggagcgcaag ttcctcgcct tctcctgccc 120

25 gctcgctggg cattatgcgg ccaagcagcc gagccccagt cctcctcctc ctcctgctcc 180
2 6 tccggctcct cctgcggccc gagcggctca gctctcggca ggcggcggcg ttgctcagcc 24 0

27 gagcgcagac gggaccctcg cagcgagacc tcagcgactc ctaaagtcaa aagttggcgg 300

28 cgggcgccgg gctccgcgcg ctctccacgg ccgctgcctc gcgtcgccgc cgcagccaag 360

29 gagggcagga gggagggggg tgggggcagc ggagggaggg gtgggaagca ccatgcagtt 4 20

30 tgtatcctgg gccacactgc taacgctcct ggtgcgggac ctggccgaga tggggagccc 480

31 agacgccgcg gcggccgtgc gcaaggacag gctgcacccg aggcaagtga aattattaga 540

32 gaccctgagc gaatacgaaa tcgtgtctcc catccgagtg aacgctctcg gagaaccctt 600

33 tcccacgaac gtccacttca aaagaacgcg acggagcatt aactctgcca ctgacccctg 660

34 gcctgccttc gcctcctcct cttcctcctc tacctcctcc caggcgcatt accgcctctc 720

35 tgccttcggc cagcagtttc tatttaatct caccgccaat gccggattta tcgctccact 780

36 gttcactgtc accctcctcg ggacgcccgg ggtgaatcag accaagtttt attccgaaga 840

37 ggaagcggaa ctcaagcact gtttctacaa aggctatgtc aataccaact ccgagcacac 900

38 ggccgtcatc agcctctgct caggaatgct gggcacattc cggtctcatg atggggatta 960

39 ttttattgaa ccactacagt ctatggatga acaagaagat gaagaggaac aaaacaaacc 1020

40 ccacatcatt tataggcgca gcgcccccca gagagagccc tcaacaggaa ggcatgcatg 1080

41 tgacacctca gaacacaaaa ataggcacag taaagacaag aagaaaacca gagcaagaaa 1140

42 atggggagaa aggattaacc tggctggtga cgtagcagca ttaaacagcg gcttagcaac 1200

43 agaggcattt tctgcttatg gtaataagac ggacaacaca agagaaaaga ggacccacag 1260

44 aaggacaaaa cgttttttat cctatccacg gtttgtagaa gtcttggtgg tggcagacaa 1320

45 cagaatggtt tcataccatg gagaaaacct tcaacactat attttaactt taatgtcaat 1380

46 tgtagcctct atctataaag acccaagtat tggaaattta attaatattg ttattgtgaa 1440

47 cttaattgtg attcataatg aacaggatgg gccttccata tcttttaatg ctcagacaac 1500

48 attaaaaaac ttttgccagt ggcagcattc gaagaacagt ccaggtggaa tccatcatga 1560

49 tactgctgtt ctcttaacaa gacaggatat ctgcagagct cacgacaaat gtgatacctt 1620

50 aggcctggct gaactgggaa ccatttgtga tccctataga agctgttcta ttagtgaaga 1680

51 tagtggattg agtacagctt ttacgatcgc ccatgagctg ggccatgtgt ttaacatgcc 174 0

52 tcatgatgac aacaacaaat gtaaagaaga aggagttaag agtccccagc atgtcatggc 1800

53 tccaacactg aacttctaca ccaacccctg gatgtggtca aagtgtagtc gaaaatatat 1860

54 cactgagttt ttagacactg gttatggcga gtgtttgctt aacgaacctg aatccagacc 1920

55 ctaccctttg cctgtccaac tgccaggcat cctttacaac gtgaataaac aatgtgaatt 1980

56 gatttttgga ccaggttctc aggtgtgccc atatatgatg cagtgcagac ggctctggtg 2040

file://C:\CRF3\Outhold\VsrI972467.htm

10/19/01

Page 2 of 7

RAW SEQUENCE LISTING DATE: 10/19/2001

PATENT APPLICATION: US/09/972,467 TIME: 12:32:07

Input Set : A:\PC10850A.app

Output Set: N:\CRF3\10192001\I972467.raw

57 caataacgtc aatggagtac acaaaggctg ccggactcag cacacaccct gggccgatgg 2100

58 gacggagtgc gagcctggaa agcactgcaa gtatggattt tgtgttccca aagaaatgga 2160

59 tgtccccgtg acagatggat cctggggaag ttggagtccc tttggaacct gctccagaac 2220

60 atgtggaggg ggcatcaaaa cagccattcg agagtgcaac agaccagaac caaaaaatgg 2280

61 tggaaaatac tgtgtaggac gtagaatgaa atttaagtcc tgcaacacgg agccatgtct 2340

62 caagcagaag cgagacttcc gagatgaaca gtgtgctcac tttgacggga agcattttaa 2400

63 catcaacggt ctgcttccca atgtgcgctg ggtccctaaa tacagtggaa ttctgatgaa 2460

64 ggaccggtgc aagttgttct gcagagtggc agggaacaca gcctactatc agcttcgaga 2520

65 cagagtgata gatggaactc cttgtggcca ggacacaaat gatatctgtg tccagggcct 2580

66 ttgccggcaa gctggatgcg atcatgtttt aaactcaaaa gcccggagag ataaatgtgg 2640

67 ggtttgtggt ggcgataatt cttcatgcaa aacagtggca ggaacattta atacagtaca 2700

68 ttatggttac aatactgtgg tccgaattcc agctggtgct accaatattg atgtgcggca 2760

69 gcacagtttc tcaggggaaa cagacgatga caactactta gctttatcaa gcagtaaagg 2820

70 tgaattcttg ctaaatggaa actttgttgt cacaatggcc aaaagggaaa ttcgcattgg 2880

71 gaatgctgtg gtagagtaca gtgggtccga gactgccgta gaaagaatta actcaacaga 2940

72 tcgcattgag caagaacttt tgcttcaggt tttgtcggtg ggaaagttgt acaaccccga 3000

73 tgtacgctat tctttcaata ttccaattga agataaacct cagcagtttt actggaacag 3060

74 tcatgggcca tggcaagcat gcagtaaacc ctgccaaggg gaacggaaac gaaaacttgt 3120

75 ttgcaccagg gaatctgatc agcttactgt ttctgatcaa agatgcgatc ggctgcccca 3180

76 gcctggacac attactgaac cctgtggtac agactgtgac ctgaggtggc atgttgccag 3240

77 caggagtgaa tgtagtgccc agtgtggctt gggttaccgc acattggaca tctactgtgc 3300

78 caaatatagc aggctggatg ggaagactga gaaggttgat gatggttttt gcagcagcca 3360
7 9 tcccaaacca agcaaccgtg aaaaatgctc aggggaatgt aacacgggtg gctggcgcta 3420

80 ttctgcctgg actgaatgtt caaaaagctg tgacggtggg acccagagga gaagggctat 3480

81 ttgtgtcaat acccgaaatg atgtactgga tgacagcaaa tgcacacatc aagagaaagt 3540

82 taccattcag aggtgcagtg agttcccttg tccacagtgg aaatctggag actggtcaga 3600

83 gtgcttggtc acctgtggaa aagggcataa gcaccgccag gtctggtgtc agtttggtga 3660

84 agatcgatta aatgatagaa tgtgtgaccc tgagaccaag ccaacatcta tgcagacttg 3720

85 tcagcagccg gaatgtgcat cctggcaggc gggtccctgg ggacagtgca gtgtcacttg 3780

86 tggacaggga taccagctaa gagcagtgaa atgcatcatt gggacttata tgtcagtggt 3840

87 agatgacaat gactgtaatg cagcaactag accaactgat acccaggact gtgaattacc 3900

88 atcatgtcat cctcccccag ctgccccgga aacgaggaga agcacataca gtgcaccaag 3960

89 aacccagtgg cgatttgggt cttggacccc atgctcagcc acttgtggga aaggtacccg 4020

90 gatgagatac gtcagctgcc gagatgagaa tggctctgtg gctgacgaga gtgcctgtgc 4080

91 taccctgcct agaccagtgg caaaggaaga atgttctgtg acaccctgtg ggcaatggaa 4140

92 ggccttggac tggagctctt gctctgtgac ctgtgggcaa ggtagggcaa cccggcaagt 4200

93 gatgtgtgtc aactacagtg accacgtgat cgatcggagt gagtgtgacc aggattatat 4260

94 cccagaaact gaccaggact gttccatgtc accatgccct caaaggaccc cagacagtgg 4320

95 cttagctcag caccccttcc aaaatgagga ctatcgtccc cggagcgcca gccccagccg 4380

96 cacccatgtg ctcggtggaa accagtggag aactggcccc tggggagcat gttccagtac 4440

97 ctgtgctggc ggatcccagc ggcgtgttgt tgtatgtcag gatgaaaatg gatacaccgc 4500

98 aaacgactgt gtggagagaa taaaacctga tgagcaaaga gcctgtgaat ccggcccttg 4560

99 tcctcagtgg gcttatggca actggggaga gtgcactaag ctgtgtggtg gaggcataag 4620

100 aacaagactg gtggtctgtc agcggtccaa cggtgaacgg tttccagatt tgagctgtga 4 680

101 aattcttgat aaacctcccg atcgtgagca gtgtaacaca catgcttgtc cacacgacgc 4740

102 tgcatggagt actggccctt ggagctcgtg ttctgtctct tgtggtcgag ggcataaaca 4800

103 acgaaatgtt tactgcatgg caaaagatgg aagccattta gaaagtgatt actgtaagca 4860

104 cctggctaag ccacatgggc acagaaagtg ccgaggagga agatgcccca aatggaaagc 4920

105 tggcgcttgg agtcagtgct ctgtgtcctg tggccgaggc gtacagcaga ggcatgtggg 4980

file://C:\CRF3\Outhold\VsrI972467.htm

10/19/01

Page 3 of 7

RAW SEQUENCE LISTING

PATENT APPLICATION: US/09/972,467

DATE: 10/19/2001
TIME: 12:32:07

Input Set : A:\PC10850A.app

Output Set: N:\CRF3\10192001\l972467.raw

1 f\c
-LU 0

c eg Lcaga cc

ggaacacaca

aaai_ay ccay

ay ay accg ay

aL^ciL^v— -ciyci^o

JU4U

1 fl7

-LU /

y y ay LCyyad

cy cyacuy

odyycci^cn^y

y uy uccccn—

+- ^ r-\ ^ n +" "h rr rr 3

yy yuay ayy a

5100

1 ft Q

atggcaagaa

tgcaccaay a

ucuyty y^y a

aygc cccay y

"t~ a r^rx r> aa^rrr

Laocy taayy

i_y y i_y cy uy c

ri fin

1 ft Q

y y a uy aCaaC

aaaaacyay y

i_y ca uy yyy c

acyc cy i_yac

y uyctycciciyi—

ygccyycyya

_> u

1 1 A

ccyT-.ya.aayc

tgtagtttgc

aaccctgcga

gtatgtctgg

atcacaggag

aatggtcaga

5280

ill
ill

ggtaccgtcc

tgggaactgt

aaccatcgtc

agctcagcca

tggectgaga

gtggcagagg

D 3 *± U

11^

gatgagtgga

gggatgagtg

caggaatgtg

ggagacttga

ggctacccgc

ccgatttgcc

s Ann

D ft U U

11 J

actgtgaact

gtgtgttttc

tgacaagtcc

tcagctttcc

caagctagaa

ttccttgtat

D ft D V

114

geaaageggg

agagatgtaa

gagatggtct

ctaagtccct

tcaggtctac

attctgtgat

DD A U

lie
115

tcaccttgat

gtcctattgg

cataaagaag

aaattattac

aggggctgea

aactcatagg

J JOU

116

atgctgtgag

gtgcctgaag

acagttaagt

ataagaaaat

attgtagtgc

cagggataca

K £ A ft

117

acaaggagag

atggcaactg

tgacaaacta

geacatgetg

tgtgaaggga

gcagaatctc

<=; 7 ft ft
J / UU

118

tttcactcca

gctgtggcca

tgcagaaatg

tggtctagcg

ttaccagacc

tgatttttca

<^ "7 £ ft

119

agagaggcta

aaaatctgga

ctagtatgtg

agatttccta

acttgaaaat

gggggctgaa

T "> A

120

atttttggtt

ttaaaacatt

gtaaggggca

aacaaacccc

tttcatgaac

cagatgtgtt

s Q ft ft

121

gtgcctgttt

aacaaacagc

ttcagaggaa

gaaaataatt

ttctataata

tccgaagtat

q a ft

122

ctcaagtac

^ Q yl Q

125

<210> SEQ ID NO

: 2

126

<211> LENGTH: 1629

127

<212> TYPE:

PRT

128

<213> ORGANISM:

Human

130

<400> SEQUENCE:

2

131

Met

Gin

Phe

Val

Ser

Trp

Ala

Thr Leu

Leu

Thr

Leu

Leu

Val

Arg

Asp

132

1

5

10

15

"1 O /I

134

Leu

Ala

Glu

Met

Gly

Ser

Pro

Asp Ala

Ala

Ala

Ala

Val

Arg

Lys

Asp

135

20

25

30

137

Arg

Leu

His

Pro

Arg

Gin

Val

Lys Leu

Leu

Glu

Thr

Leu

Ser

Glu

Tyr

138

35

40

45

1 A ft

14 U

Glu

He

Val

Ser

Pro

He

Arg

Val Asn

Ala

Leu

Gly

Glu

Pro

Phe

Pro

141

50

55

60

1 A O

143

Thr

Asn

Val

His

Phe

Lys

Arg

Thr Arg

Arg

Ser

He

Asn

Ser

Ala

Thr

144

65

70

75

80

14b

Asp

Pro

Trp

Pro

Ala

Phe

Ala

Ser Ser

Ser

Ser

Ser

Ser

Thr

Ser

Ser

147

85

90

95

149

Gin

Ala

His

Tyr

Arg

Leu

Ser

Ala Phe

Gly

Gin

Gin

Phe

Leu

Phe

Asn

1 C A

150

100

105

110

Leu

Thr

Ala

Asn

Ala Gly

Phe

He Ala

Pro

Leu

Phe

Thr

Val

Thr

Leu

153

115

120

125

155

Leu

Gly

Thr

Pro

Gly Val

Asn

Gin Thr

Lys

Phe

Tyr

Ser

Glu

Glu

Glu

156

130

135

140

158

Ala

Glu

Leu

Lys

His

Cys

Phe

Tyr Lys

Gly

Tyr

Val

Asn

Thr

Asn

Ser

159

145

150

155

160

161

Glu

His

Thr

Ala

Val

He

Ser

Leu Cys

Ser

Gly

Met

Leu

Gly

Thr

Phe

162

165

170

175

164

Arg

Ser

His

Asp

Gly

Asp

Tyr

Phe He

Glu

Pro

Leu

Gin

Ser

Met

Asp

165

180

185

190

167

Glu

Gin

Glu

Asp

Glu

Glu

Glu

Gin Asn

Lys

Pro

His

He

He

Tyr

Arg

168

195

200

205

170

Arg

Ser

Ala

Pro

Gin

Arg

Glu

Pro Ser

Thr

Gly

Arg

His

Ala

Cys

Asp

file://C:\CRF3\Outhold\VsrI972467.htm

10/19/01

Page 4 of 7

171 210

RAW SEQUENCE LISTING DATE: 10/19/2001

PATENT APPLICATION: US/09/972,467 TIME: 12:32:07

Input Set : A:\PC10850A.app
Output Set: N:\CRF3\10192001\I972467.raw

215 220

173 Thr Ser Glu His Lys Asn Arg His Ser Lys Asp Lys Lys Lys Thr Arg

174 225 230 235 240

176 Ala Arg Lys Trp Gly Glu Arg He Asn Leu Ala Gly Asp Val Ala Ala

177 245 250 255

179 Leu Asn Ser Gly Leu Ala Thr Glu Ala Phe Ser Ala Tyr Gly Asn Lys

180 260 265 270

182 Thr Asp Asn Thr Arg Glu Lys Arg Thr His Arg Arg Thr Lys Arg Phe

183 275 280 285

185 Leu Ser Tyr Pro Arg Phe Val Glu Val Leu Val Val Ala Asp Asn Arg

186 290 295 300

188 Met Val Ser Tyr His Gly Glu Asn Leu Gin His Tyr He Leu Thr Leu

189 305 310 315 320 .

191 Met Ser He Val Ala Ser He Tyr Lys Asp Pro Ser He Gly Asn Leu

192 325 330 335

194 He Asn He Val He Val Asn Leu He Val He His Asn Glu Gin Asp

195 340 345 350

197 Gly Pro Ser He Ser Phe Asn Ala Gin Thr Thr Leu Lys Asn Phe Cys

198 355 360 365

200 Gin Trp Gin His Ser Lys Asn Ser Pro Gly Gly He His His Asp Thr

201 370 375 380

203 Ala Val Leu Leu Thr Arg Gin Asp He Cys Arg Ala His Asp Lys Cys

204 385 390 395 400

206 Asp Thr Leu Gly Leu Ala Glu Leu Gly Thr He Cys Asp Pro Tyr Arg

207 405 410 415

209 Ser Cys Ser He Ser Glu Asp Ser Gly Leu Ser Thr Ala Phe Thr He

210 420 425 430

212 Ala His Glu Leu Gly His Val Phe Asn Met Pro His Asp Asp Asn Asn

213 435 440 445

215 Lys Cys Lys Glu Glu Gly Val Lys Ser Pro Gin His Val Met Ala Pro

216 450 455 460

218 Thr Leu Asn Phe Tyr Thr Asn Pro Trp Met Trp Ser Lys Cys Ser Arg

219 465 470 475 480

221 Lys Tyr He Thr Glu Phe Leu Asp Thr Gly Tyr Gly Glu Cys Leu Leu

222 485 490 495

224 Asn Glu Pro Glu Ser Arg Pro Tyr Pro Leu Pro Val Gin Leu Pro Gly

225 500 505 510 •

227 He Leu Tyr Asn Val Asn Lys Gin Cys Glu Leu He Phe Gly Pro Gly

228 515 520 525

230 Ser Gin Val Cys Pro Tyr Met Met Gin Cys Arg Arg Leu Trp Cys Asn

231 530 535 540

233 Asn Val Asn Gly Val His Lys Gly Cys Arg Thr Gin His Thr Pro Trp

234 545 550 555 560

236 Ala Asp Gly Thr Glu Cys Glu Pro Gly Lys His Cys Lys Tyr Gly Phe

237 565 570 575

239 Cys Val Pro Lys Glu Met Asp Val Pro Val Thr Asp Gly Ser Trp Gly

240 580 585 590

242 Ser Trp Ser Pro Phe Gly Thr Cys Ser Arg Thr Cys Gly Gly Gly He

243 595 600 605

file://C:\CRF3\Outhold\VsrI972467.htm

10/19/01

RAW SEQUENCE LISTING DATE: 10/19/2001

PATENT APPLICATION: US/09/972 , 467 TIME: 12:32:08

Input Set : A:\PCl0850A.app

Output Set: N:\CRF3\10192001\I972467.raw

245

Lys

Thr

Ala

He

Arg

Glu

Cys

Asn

Arg

Pro

Glu

Pro

Lys

Asn

Gly

Gly

246

610

615

620

248

Lys

Tyr

Cys

Val

Gly

Arg

Arg

Met

Lys

Phe

Lys

Ser

Cys

Asn

Thr

Glu

249

625

630

635

640

251

Pro

Cys

Leu

Lys

Gin

Lys

Arg

Asp

Phe

Arg

Asp

Glu

Gin

Cys

Ala

His

252

645

650

655

254

Phe

Asp

Gly

Lys

His

Phe

Asn

He

Asn

Gly

Leu

Leu

Pro

Asn

Val

Arg

255

660

665

670

257

Trp

Val

Pro

Lys

Tyr

Ser

Gly

He

Leu

Met

Lys

Asp

Arg

Cys

Lys

Leu

258

675

680

685

260

Phe

Cys

Arg

Val

Ala

Gly

Asn

Thr

Ala

Tyr

Tyr

Gin

Leu

Arg

Asp

Arg

261

690

695

700

263

Val

He Asp Gly

Thr

Pro

Cys

Gly

Gin

Asp

Thr

Asn

Asp

He

cys

Val

264

705

710

715

720

266

Gin

Gly

Leu

Cys

Arg

Gin

Ala

Gly

Cys

Asp

His

Val

Leu

Asn

Ser

Lys

267

725

730

735

269

Ala

Arg

Arg

Asp

Lys

Cys

Gly

Val

Cys

Gly

Gly

Asp

Asn

Ser

Ser

Cys

270

740

745

750

272

Lys

Thr

Val

Ala

Gly

Thr

Phe

Asn

Thr

Val

His

Tyr

Gly

Tyr

Asn

Thr

273

755

760

765

275

Val

Val

Arg

He

Pro

Ala

Gly

Ala

Thr

Asn

He

Asp

Val

Arg

Gin

His

276

770

775

780

278

Ser

Phe

Ser Gly

Glu

Thr

Asp

Asp

Asp

Asn

Tyr

Leu

Ala

Leu

Ser

Ser

279

785

790

795

800

281

Ser Lys Gly Glu

Phe

Leu

Leu

Asn

Gly

Asn

Phe

Val

Val

Thr

Met

Ala

282

805

810

815

284

Lys

Arg

Glu

He

Arg

He

Gly

Asn

Ala

Val

Val

Glu

Tyr

Ser

Gly

Ser

285

820

825

830

287

Glu

Thr

Ala

Val

Glu

Arg

He

Asn

Ser

Thr

Asp

Arg

He

Glu

Gin

Glu

288

835

840

845

290

Leu

Leu

Leu

Gin

Val

Leu

Ser

Val

Gly

Lys

Leu

Tyr

Asn

Pro

Asp

Val

291

850

855

860

293

Arg

Tyr

Ser

Phe

Asn

He

Pro

He

Glu

Asp

Lys

Pro

Gin

Gin

Phe

Tyr

294

865

870

875

880

296

Trp

Asn

Ser

His

Gly

Pro

Trp

Gin

Ala

Cys

Ser

Lys

Pro

Cys

Gin

Gly

297

885

890

895

299

Glu

Arg

Lys

Arg

Lys

Leu

Val

Cys

Thr

Arg

Glu

Ser

Asp

Gin

Leu

Thr

300

900

905

910

302

Val

Ser Asp

Gin

Arg

Cys

Asp

Arg

Leu

Pro

Gin

Pro

Gly

His

He

Thr

303

915

920

925

305

Glu

Pro

Cys

Gly

Thr

Asp

Cys

Asp

Leu

Arg

Trp

His

Val

Ala

Ser

Arg

306

930

935

940

308

Ser

Glu

Cys

Ser

Ala

Gin

Cys

Gly

Leu

Gly

Tyr

Arg

Thr

Leu

Asp

He

309

945

950

955

960

311

Tyr

Cys

Ala

Lys

Tyr

Ser

Arg

Leu

Asp

Gly

Lys

Thr

Glu

Lys

Val

Asp

312

965

970

975

314

Asp

Gly

Phe

Cys

Ser

Ser

His

Pro

Lys

Pro

Ser

Asn

Arg

Glu

Lys

Cys

315

980

985

990

317

Ser Gly

Glu

Cys

Asn

Thr

Gly

Gly

Trp

Arg

Tyr

Ser

Ala

Trp

Thr

Glu

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VERIFICATION SUMMARY DATE: 10/19/2001

PATENT APPLICATION: US/09/972,467 TIME: 12:32:09

Input Set : A:\PC10850A.app

Output Set: N:\CRP3\10192001\l972467.raw

L-10 M-270 C: Current Application Number differs, Replaced Application Number
L:ll M:271 C: Current Filing Date differs, Replaced Current Filing Date

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10/19/01